僅用于工業(yè)應(yīng)用或科學(xué)研究，不可用于人類或動物的臨床診斷或治療，非藥用.XAV-939 is a Tankyrase inhibitor. XAV-939 has inhibitory activity for TNKS1 and TNKS2 with IC50 values of 5 nM and 2 nM, respectively. XAV-939 also is an enhancer of osteoblastic differentiation of hMSCs. XAV-939 can be used for the research of conditions associated with activated Wnt signaling, such as cancer, fibrotic diseases and conditions associated with low bone formation.XAV-939 是一種 Tankyrase 抑制劑。XAV-939 對 TNKS1 和 TNKS2 具有抑制活性，IC50 值分別為 5 nM 和 2 nM。XAV-939 也是 hMSCs 成骨細胞分化的增強劑。XAV-939 可用于研究與激活的 Wnt 信號傳導(dǎo)相關(guān)的疾病